宮頸癌機會性篩查的應用與分析

【摘要】論文目的:探討宮頸癌機會性篩查的應用及意義。論文方法:為2008年1月~12月在新疆自治區(qū)人民醫(yī)院婦產(chǎn)科門診就診的患者行機會性篩查,以液基細胞學、HPV檢測和陰道鏡為篩查方法,活檢組織病理學診斷為最終診斷標準,評價機會性篩查用于宮頸癌早診、早治的意義。結果:4485例患者中一半以上患者不了解宮頸癌相關知識;患者篩查順應性為98. 79% (4431/4485),檢出細胞學陽性569例,陽性檢出率12. 68% (569/4485); 561例行高危HPV檢測,感染率36. 54% (205/561); 549例行陰道鏡+活檢,活檢病理結果為: CINⅠ62例, CINⅡ-Ⅲ46例、SCC 8例。2008年宮頸癌篩查參與率及宮頸病變檢出率與2007年同期比較差異有統(tǒng)計學意義(P<0. 05)。結論:通過機會性篩查相關干預措施有助于提高患者對宮頸癌的認知程度,是全面防治宮頸癌的重要內(nèi)容;機會性篩查順應性好,能夠早期發(fā)現(xiàn)宮頸病變,是行之有效的宮頸癌篩查方法,值得推廣應用?！　?br /> 【關鍵詞】宮頸腫瘤;機會性篩查;液基細胞學檢查;人乳頭瘤病毒　　

The application and significance of opportunistic screening for cervical cancer
【Abstract】　Objective:To discuss the application and significance of opportunisticscreening for cervical cancer.M ethods:Patientswhowere visiting in the department ofGyne-cology of the Peoples' Hospital ofXinjiangwere performed with opportunistic screening-relatedinterventions. Screeningmethod included Thinprep CytologyTes,tHPV testing and colposcopy.The final pathological diagnosis of cervical biopsy was as the diagnostic criteria to assess themeaning of the opportunistic screening for cervical cancer at early diagnosis.Results:Among4485 cases, a halfof the patients didnt' know the knowledge of cervical cancer; screening com-pliancewas 98. 79%.AbnormalTCT results rate was 12. 68% (569/4485).The infection rateofHR-HPV was36. 54% (205/561).Biopsy resultswere as follows:CINⅠ62 cases,CINⅡ~Ⅲ46 cases, SCC 8 cases.There was statistical difference(P<0. 05)between 2008 and 2007two years in cervical lesionsdetection rate.Conclusion:In screening, to raise the cognition lev-el of cervical cancer is important for comprehensive prevention and control of cervical cancer.The opportunistic screening for cervical cancer is effective and economica.l Itcan recognize cer-vical lesions earlywith high screening compliance.　　
【Keywords】Cervix neoplasms;Opportunistic screening;Thinprep cytology tes;tHumanpapillomavirus