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腦部定量核磁共振灌注成像-------外文翻譯.doc

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腦部定量核磁共振灌注成像-------外文翻譯,purpose:to eva luatequantitativecerebralbloodflow (qcbf) with traditional time-based measurements or metrics of cerebral perfusion: time to peak (tmax) an...
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Purpose: To eva luate quantitative cerebral blood flow (qCBF) with traditional time-based measurements or metrics of cerebral perfusion: time to peak (Tmax) and mean

transit time (MTT) in stroke patients.

Materials and Methods: Nine ischemic stroke patients (four male, five female, 63 6 16 years old) were included in the study which was Health Insurance Portability and

Accountability Act compliant and institutional review board approved. Cerebral perfusion was quantified using the Bookend method. Mean values of qCBF, Tmax, and MTT were determined in regions of interest (ROIs). ROIs were drawn on diffusion weighted images in diffusion positive, critically ischemic (CI), in ipsilateral normal region immediately surrounding the critically ischemic region,the presumed penumbra (PP), and in contralateral diffusion negative control, presumed normal region (PN) of gray and white matter separately (GM and WM).

目的:采用傳統(tǒng)的基于時間的腦灌注測量或度量方法,定量評估腦血流量:腦卒中病人腦血流量的達峰的時間(Tmax)和平均通過時間(MTT)。

材料和方法:經(jīng)過了機構審查委員會批準并遵循醫(yī)療保險便利及責任法案,本研究納入9名缺血性腦卒中病人(4名男性,5名女性,年齡為63±16)。使用書夾法對腦灌注進行定量分析。測定了感興趣區(qū)域(ROIs)的腦血流量均值、最大峰值時間和平均通過時間。感興趣區(qū)域包括彌散陽性區(qū)以及嚴重缺血區(qū)域的彌散加權成像,迅速波